A joint committee of the Society of Surgical Oncology and the American Society of Clinical Oncology recently issued an evidence-based guideline that recommends sentinel-node biopsy for patients with intermediate-thickness melanomas and consideration of the procedure for patients with thick melanomas. Our current report, which provides the final long-term follow-up data from a randomized, international clinical trial of sentinel-node biopsy versus observation, augments the evidence base for the use of sentinel-node biopsy in such patients.


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